Cytofluorometric detection of human endothelial cells in whole blood using S-Endo 1 monoclonal antibody
F George, P Poncelet, JC Laurent, O Massot… - Journal of …, 1991 - Elsevier
It has long been debated whether endothelial cells are present at very low frequency in
peripheral blood. Elevated concentrations of such circulating cells may present a good
marker of vascular injury. We have therefore designed an immunocytometric assay for the
detection of rare endothelial cells in whole blood. This assay is based on a new monoclonal
antibody (MAb) S-Endo 1, made against human umbilical vein endothelial cells (HUVEC)
and specific for endothelial cells of various origins without detectable reactivity with blood …
peripheral blood. Elevated concentrations of such circulating cells may present a good
marker of vascular injury. We have therefore designed an immunocytometric assay for the
detection of rare endothelial cells in whole blood. This assay is based on a new monoclonal
antibody (MAb) S-Endo 1, made against human umbilical vein endothelial cells (HUVEC)
and specific for endothelial cells of various origins without detectable reactivity with blood …