Atypical pneumonitis, often induced by infection with Mycoplasma pneumoniae, is frequently
associated with elevated cold agglutinin titers but only rarely with significant hemolytic
anemia. An example and documentation of the clinical and immunologic course of such
transient cold agglutinin hemolytic anemia is presented, and the immunochemical
characteristics of cold agglutinins in this syndrome are assessed in regard to their biologic
implications and diagnostic significance. Transient cold agglutinins, such as observed in this …