[HTML][HTML] Molecular cloning and identification of N-acyl-D-glucosamine 2-epimerase from porcine kidney as a renin-binding protein
I Maru, Y Ohta, K Murata, Y Tsukada - Journal of Biological Chemistry, 1996 - ASBMB
N-Acetylneuraminic acid (NeuAc) is an important molecule in biological recognition systems.
NeuAc is known to be biosynthesized either from UDP-N-acetyl-D-glucosamine by an action
of UDP-N-acetyl-D-glucosamine 2-epimerase or from N-acetyl-D-glucosamine by N-acyl-D-
glucosamine 2-epimerase (GlcNAc 2-epimerase). However, the physiological function of the
GlcNAc 2-epimerase in NeuAc biosynthesis has not been fully evaluated. To clarify the role
of GlcNAc 2-epimerase in NeuAc biosynthesis, the enzyme and its gene were isolated from …
NeuAc is known to be biosynthesized either from UDP-N-acetyl-D-glucosamine by an action
of UDP-N-acetyl-D-glucosamine 2-epimerase or from N-acetyl-D-glucosamine by N-acyl-D-
glucosamine 2-epimerase (GlcNAc 2-epimerase). However, the physiological function of the
GlcNAc 2-epimerase in NeuAc biosynthesis has not been fully evaluated. To clarify the role
of GlcNAc 2-epimerase in NeuAc biosynthesis, the enzyme and its gene were isolated from …