Effects of hydrophobicity on turnover of plasma high density lipoproteins labeled with phosphatidylcholine ethers in the rat
HJ Pownall, D Hickson-Bick, JB Massey - Journal of lipid research, 1991 - ASBMB
Rat high density lipoproteins (HDL) were labeled with a series of phosphatidylcholines and
ether analogs of phosphatidylcholine. The rates of turnover of the phosphatidylcholine
ethers in the rat decreased as a function of increasing hydrophobicity and were more than
five times faster than those of apolipoprotein AI turnover and spontaneous lipid transfer. The
major tissue sites for uptake were the liver, adrenals, and ovaries. The rate of turnover of a
phosphatidylcholine was faster than that of the corresponding ether analog due to the action …
ether analogs of phosphatidylcholine. The rates of turnover of the phosphatidylcholine
ethers in the rat decreased as a function of increasing hydrophobicity and were more than
five times faster than those of apolipoprotein AI turnover and spontaneous lipid transfer. The
major tissue sites for uptake were the liver, adrenals, and ovaries. The rate of turnover of a
phosphatidylcholine was faster than that of the corresponding ether analog due to the action …