Recent insights into kidney diseases associated with glomerular cysts
AS Woolf, SA Feather, C Bingham - Pediatric nephrology, 2002 - Springer
AS Woolf, SA Feather, C Bingham
Pediatric nephrology, 2002•SpringerGlomerular cysts can exist in the context of several different kidney diseases. Advances in
the last few years have begun to unravel the genetic bases and pathogenesis of some of
these entities, many of which have an origin in abnormal development. In this review, we
highlight recent insights into three types of disease associated with glomerular cysts:(1)
mutations of the hepatocyte nuclear factor 1β (HNF-1β) in the recently described renal cysts
and diabetes syndrome,(2) mutations of OFD1 in the oral facial digital syndrome type 1 and …
the last few years have begun to unravel the genetic bases and pathogenesis of some of
these entities, many of which have an origin in abnormal development. In this review, we
highlight recent insights into three types of disease associated with glomerular cysts:(1)
mutations of the hepatocyte nuclear factor 1β (HNF-1β) in the recently described renal cysts
and diabetes syndrome,(2) mutations of OFD1 in the oral facial digital syndrome type 1 and …
Abstract
Glomerular cysts can exist in the context of several different kidney diseases. Advances in the last few years have begun to unravel the genetic bases and pathogenesis of some of these entities, many of which have an origin in abnormal development. In this review, we highlight recent insights into three types of disease associated with glomerular cysts: (1) mutations of the hepatocyte nuclear factor 1β (HNF-1β) in the recently described renal cysts and diabetes syndrome, (2) mutations of OFD1 in the oral facial digital syndrome type 1 and (3) the role of fetal urinary tract obstruction.
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