The presenting manifestations of Lyme disease and the outcomes of treatment

AC Steere, VK Sikand - New England Journal of Medicine, 2003 - Mass Medical Soc
AC Steere, VK Sikand
New England Journal of Medicine, 2003Mass Medical Soc
To the Editor: A trial of vaccination against Lyme disease provided an opportunity for us to
determine the relative frequencies of the presenting manifestations of Lyme disease and the
outcomes of treatment in a large population. 1 Our goal was to identify all cases of Borrelia
burgdorferi infection that occurred among the 10,936 participants in 10 states where the
infection is endemic during the 20-month study period. Of the 1917 participants who were
evaluated for Lyme disease, 269 met the prospectively defined criteria for definite, possible …
To the Editor: A trial of vaccination against Lyme disease provided an opportunity for us to determine the relative frequencies of the presenting manifestations of Lyme disease and the outcomes of treatment in a large population.1 Our goal was to identify all cases of Borrelia burgdorferi infection that occurred among the 10,936 participants in 10 states where the infection is endemic during the 20-month study period.
Of the 1917 participants who were evaluated for Lyme disease, 269 met the prospectively defined criteria for definite, possible, or asymptomatic infection.1 After completion of the study, post hoc analyses were performed for patients . . .
The New England Journal Of Medicine