Tec family kinases in lymphocyte signaling and function
EM Schaeffer, PL Schwartzberg - Current opinion in immunology, 2000 - Elsevier
Current opinion in immunology, 2000•Elsevier
The Tec kinases are required for full Ca2+ mobilization in lymphocytes. Recent data suggest
that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells
and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec
kinases in lymphocyte development and function.
that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells
and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec
kinases in lymphocyte development and function.
The Tec kinases are required for full Ca2+ mobilization in lymphocytes. Recent data suggest that this process occurs via a multiprotein complex that includes LAT and SLP-76 in T cells and BLNK/SLP-65 in B cells. Mutational analyses have revealed critical roles for Tec kinases in lymphocyte development and function.
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