C/EBP and the control of phosphoenolpyruvate carboxykinase gene transcription in the liver

C Croniger, P Leahy, L Reshef, RW Hanson - Journal of Biological …, 1998 - ASBMB
In 1989, shortly after the discovery of CAAT/enhancer-binding protein (C/EBP) 1 and in a
period before it was clear that there was more than one form of C/EBP, McKnight et al.(1)
published a review entitled:“Is C/EBP a Central Regulator of Energy Metabolism?” This
prediction of a critical metabolic role for this transcription factor was based on the very slim
evidence that C/EBP was involved in the transcription of a number of metabolically important
genes such as 422/aP2, phosphoenolpyruvate carboxykinase (PEPCK), and fatty acid …