The complement system in bullous pemphigoid: IV. Chemotactic activity in blister fluid

JL Diaz-Perez, RE Jordon - Clinical Immunology and Immunopathology, 1976 - Elsevier
By a modified Boyden technique, chemotactic activity was present in bullous pemphigoid
blister fluids but was also present in the corresponding sera. Heat inactivation (56° C for 30
min) only partially reduced the chemotactic activity of the blister fluid but almost completely
inhibited the activity in pemphigoid sera. Both suction-induced and cantharidin-induced
blister fluids exhibited some chemotactic activity but, in contrast to pemphigoid blister fluids,
this activity was almost entirely abolished by heat inactivation. Blister fluids from some …