Neurofibromatosis 1 (NFl) is a neurocutaneous disorder with a panethnic incidence of
approximately 1 in 3000.1 It is inherited in an autosomal dominant fashion and has an equal
sex incidence. The cardinal features of NF1 are cafk au lait spots, axillary freckling,
cutaneous neurofibromas, and iris hamartomas (Lisch nodules). However, NFl is also a
multisystem disorder with a wide variety of disease manifestations affecting the eyes, bony
skeleton, endocrine system and blood vessels, as well as the central and peripheral nervous …