The science and therapy of glucocorticoid-induced bone loss

NE Lane, B Lukert - Endocrinology and metabolism clinics of North America, 1998 - Elsevier
Glucocorticoids are widely used in the treatment of patients with chronic noninfectious
inflammatory diseases, especially asthma, chronic lung disease, rheumatoid arthritis, other
connective tissue diseases, and inflammatory bowel disease, and in organ transplantation.
The important anti-inflammatory and immunosuppressive properties of this class of drugs
have prompted their extensive use; however, complications are many, and bone loss
resulting in vertebral fractures is the most incapacitating effect. Because of their extensive …