A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2.

MB Parr, L Kepple, MR McDermott… - … ; a journal of technical …, 1994 - europepmc.org
MB Parr, L Kepple, MR McDermott, MD Drew, JJ Bozzola, EL Parr
Laboratory investigation; a journal of technical methods and pathology, 1994europepmc.org
Background The role of mucosal immunity in defense of the female genital tract against
pathogens such as herpes simplex virus-2 (HSV-2) is poorly understood. Here we explored
the use of a new mouse model to determine whether local immune events in the vagina of
immune animals may protect them against genital herpes.
Background
The role of mucosal immunity in defense of the female genital tract against pathogens such as herpes simplex virus-2 (HSV-2) is poorly understood. Here we explored the use of a new mouse model to determine whether local immune events in the vagina of immune animals may protect them against genital herpes.
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