The purpose of this study was to outline the fertility features of non-obese diabetic
(NOD)/LtSz-scid/scid (NOD/SCID [severe combined immunodeficiency] for short) mice, and
to evaluate the effects of NK cell subsets on the pregnancy outcomes of the syngeneic
NOD/SCID× NOD/SCID mating combination. Firstly, lymphocyte phenotyping was performed
with flow cytometry to confirm the multiple immunodeficits in NOD/SCID mice. Fertility
features were assessed in NOD/SCID× NOD/SCID mice and compared with non …