Diagnosis and initial management of Parkinson's disease

JG Nutt, GF Wooten - New England Journal of Medicine, 2005 - Mass Medical Soc
JG Nutt, GF Wooten
New England Journal of Medicine, 2005Mass Medical Soc
Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of
formal guidelines, when they exist. The article ends with the authors' clinical
recommendations. Stage A 62-year-old man presents with an intermittent tremor in his left
hand and some vague discomfort in the left arm. Physical examination shows a minimal rest
tremor in the left hand that disappears with use of the limb, mild rigidity at the left wrist and …
Foreword
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.
Stage
A 62-year-old man presents with an intermittent tremor in his left hand and some vague discomfort in the left arm. Physical examination shows a minimal rest tremor in the left hand that disappears with use of the limb, mild rigidity at the left wrist and elbow, slowness of finger tapping with the left hand, and decreased arm swing on the left while walking. How should he be evaluated and treated?
The Clinical Problem
Parkinsonism, the syndrome, is a common movement disorder, and Parkinson's disease, the most common cause of parkinsonism, is the second most prevalent neurodegenerative disease after Alzheimer's . . .
The New England Journal Of Medicine