Identification of far upstream element-binding protein-1 as an authentic Parkin substrate
Aminoacyl-tRNA synthetase-interacting multifunctional protein type 2 was recently identified
as an authentic substrate of the ubiquitin E3 ligase, parkin, a gene associated with
autosomal recessive juvenile parkinsonism. Far upstream element-binding protein 1 is
known to be degraded in an aminoacyl-tRNA synthetase interacting multifunctional protein
type 2 dependent manner, which is crucial for lung cell maturation in early development.
Therefore, we wondered whether far upstream element-binding protein 1 levels are altered …
as an authentic substrate of the ubiquitin E3 ligase, parkin, a gene associated with
autosomal recessive juvenile parkinsonism. Far upstream element-binding protein 1 is
known to be degraded in an aminoacyl-tRNA synthetase interacting multifunctional protein
type 2 dependent manner, which is crucial for lung cell maturation in early development.
Therefore, we wondered whether far upstream element-binding protein 1 levels are altered …
