A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay
C Helma, M Uhl - Mutation Research/Genetic Toxicology and …, 2000 - Elsevier
The single-cell gel electrophoresis (or comet) assay has gained widespread acceptance as
a cheap and simple genotoxicity test, but it requires a computer-assisted image-analysis
system. As commercial programs are expensive and inflexible, we decided to develop an
image-analysis system based on public domain programs and make it publicly available for
the scientific community. Our system is based on the scientific image-processing program
NIH Image, and was written in its Pascal-like macro language. User interaction was kept as …
a cheap and simple genotoxicity test, but it requires a computer-assisted image-analysis
system. As commercial programs are expensive and inflexible, we decided to develop an
image-analysis system based on public domain programs and make it publicly available for
the scientific community. Our system is based on the scientific image-processing program
NIH Image, and was written in its Pascal-like macro language. User interaction was kept as …