The clinical success of new treatment strategies aiming on inducing permanent graft
acceptance will rely on the ability to determine whether specific unresponsiveness to donor
alloantigens has developed and for how long it is maintained. To identify markers for such
posttransplant monitoring, genes differentially expressed by graft infiltrating leukocytes
during tolerance induction or rejection after kidney transplantation in rats were compared. A
subsequently performed full kinetic analysis in two different transplant models, kidney and …