Delta‐9‐tetrahydrocannabinol and glucose tolerance
LE Hollister, GM Reaven - Clinical Pharmacology & …, 1974 - Wiley Online Library
LE Hollister, GM Reaven
Clinical Pharmacology & Therapeutics, 1974•Wiley Online LibraryIntravenous doses of 6 mg of delta‐9‐tetrahydrocannabinol (THC) produced moderately
severe marihuana intoxications. Glucose tolerance was impaired, and this deterioration of
glucose tolerance was associated with increased plasma levels of growth hormone.
Although large doses of marihuana might aggravate diabetes, the rarity of this phenomenon
in clinical practice may be due to the lower doses of THC used socially or development of
tolerance to this specific pharmacologic effect.
severe marihuana intoxications. Glucose tolerance was impaired, and this deterioration of
glucose tolerance was associated with increased plasma levels of growth hormone.
Although large doses of marihuana might aggravate diabetes, the rarity of this phenomenon
in clinical practice may be due to the lower doses of THC used socially or development of
tolerance to this specific pharmacologic effect.
Intravenous doses of 6 mg of delta‐9‐tetrahydrocannabinol (THC) produced moderately severe marihuana intoxications. Glucose tolerance was impaired, and this deterioration of glucose tolerance was associated with increased plasma levels of growth hormone. Although large doses of marihuana might aggravate diabetes, the rarity of this phenomenon in clinical practice may be due to the lower doses of THC used socially or development of tolerance to this specific pharmacologic effect.
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