Recent advances in mammalian RFamide peptides: the discovery and functional analyses of PrRP, RFRPs and QRFP
S Fukusumi, R Fujii, S Hinuma - Peptides, 2006 - Elsevier
Since the first discovery of a peptide with RFamide structure at its C-terminus (ie, an
RFamide peptide) from an invertebrate in 1977, numerous studies on RFamide peptides
have been conducted, and a variety have been identified in various phyla throughout the
animal kingdom. The first reported mammalian RFamide peptides were neuropeptide FF
(NPFF) and neuropeptide AF (NPAF) in 1985. However, for many years after this, no new
novel RFamide peptides were identified in mammals. A breakthrough in discovering …
RFamide peptide) from an invertebrate in 1977, numerous studies on RFamide peptides
have been conducted, and a variety have been identified in various phyla throughout the
animal kingdom. The first reported mammalian RFamide peptides were neuropeptide FF
(NPFF) and neuropeptide AF (NPAF) in 1985. However, for many years after this, no new
novel RFamide peptides were identified in mammals. A breakthrough in discovering …