Discontinuance of immunosuppression in renal transplant patients
ML Owens, JG Maxwell, J Goodnight… - Archives of …, 1975 - jamanetwork.com
• Immunosuppressive therapy was discontinued in six patients for an average of 27 months.
In these six patients, only two rejections have occurred. A survey of other transplant centers
showed that in such patients rejection was often delayed weeks or months after therapy was
stopped. Once immunosuppressive therapy has been stopped, for whatever reason, and
rejection has not occurred, consideration should be given to not resuming therapy unless
signs of rejection appear.(Arch Surg110: 1450-1451, 1975)
In these six patients, only two rejections have occurred. A survey of other transplant centers
showed that in such patients rejection was often delayed weeks or months after therapy was
stopped. Once immunosuppressive therapy has been stopped, for whatever reason, and
rejection has not occurred, consideration should be given to not resuming therapy unless
signs of rejection appear.(Arch Surg110: 1450-1451, 1975)
