[HTML][HTML] Clinical operational tolerance after kidney transplantation

G Roussey-Kesler, M Giral, A Moreau, JF Subra… - American Journal of …, 2006 - Elsevier
Induction of allograft-specific tolerance and the detection of a “tolerance” state in recipients
under immunosuppression with long-term stable graft function are major challenges in
transplantation. Clinical “operational tolerance,” defined as stable and acceptable graft
function without immunosuppression for years, is a rare event. There is no report on the
clinical history of such patients. In this article, we report on the medical history of 10 kidney
recipients who display an immunosuppressive drug-free “operational tolerance” for 9.4±5.2 …