Anandamide metabolism by Tetrahymena pyriformis in vitro. Characterization and identification of a 66 kDa fatty acid amidohydrolase
V Karava, PM Zafiriou, L Fasia, D Anagnostopoulos… - Biochimie, 2005 - Elsevier
Fatty acid amidohydrolase, a membrane-bound enzyme found in a variety of mammalian
cells, is responsible for the catabolism of neuromodulatory fatty acid amides, including
anandamide. In an earlier study we reported that Tetrahymena pyriformis was able to
secrete a FAAH-like activity in starvation medium (Karava V., Fasia L., Siafaka-Kapadai A.,
FEBS Lett. 508 (2001) 327–331). In this study the endocannabinoid anandamide, was found
to be metabolized by T. pyriformis homogenate by the action of a FAAH-like enzyme, in a …
cells, is responsible for the catabolism of neuromodulatory fatty acid amides, including
anandamide. In an earlier study we reported that Tetrahymena pyriformis was able to
secrete a FAAH-like activity in starvation medium (Karava V., Fasia L., Siafaka-Kapadai A.,
FEBS Lett. 508 (2001) 327–331). In this study the endocannabinoid anandamide, was found
to be metabolized by T. pyriformis homogenate by the action of a FAAH-like enzyme, in a …