Lesions of primary and secondary syphilis contain activated cytolytic T cells
WC van Voorhis, LK Barrett, JM Nasio… - Infection and …, 1996 - Am Soc Microbiol
WC van Voorhis, LK Barrett, JM Nasio, FA Plummer, SA Lukehart
Infection and immunity, 1996•Am Soc MicrobiolThis study demonstrates that CD8+ cytotoxic lymphocytes (CTL) are found in both primary
and secondary syphilis lesions. CD8+ T cells were detected by immunohistology, and
mRNAs for granzyme B and perforin were detected by reverse transcription and PCR,
suggesting that CD8+ cytotoxic lymphocytes are activated.
and secondary syphilis lesions. CD8+ T cells were detected by immunohistology, and
mRNAs for granzyme B and perforin were detected by reverse transcription and PCR,
suggesting that CD8+ cytotoxic lymphocytes are activated.
This study demonstrates that CD8+ cytotoxic lymphocytes (CTL) are found in both primary and secondary syphilis lesions. CD8+ T cells were detected by immunohistology, and mRNAs for granzyme B and perforin were detected by reverse transcription and PCR, suggesting that CD8+ cytotoxic lymphocytes are activated.
American Society for Microbiology