[HTML][HTML] Activation of Gsα by the Epidermal Growth Factor Receptor Involves Phosphorylation (∗)
H Poppleton, H Sun, D Fulgham, P Bertics… - Journal of Biological …, 1996 - ASBMB
Previous studies from our laboratory have shown that epidermal growth factor (EGF)
stimulates cAMP accumulation in the heart via a process involving G sα and the EGF
receptor (EGFR) protein tyrosine kinase activity (Nair, BG, Parikh, B., Milligan, G., and Patel,
TB (1990) J. Biol. Chem. 265, 21317-21322; Nair, BG, and Patel, TB (1993) Biochem.
Pharmacol. 46, 1239-1245). Therefore, studies were performed to investigate the hypothesis
that the EGFR protein tyrosine kinase phosphorylates G sα and activates this protein …
stimulates cAMP accumulation in the heart via a process involving G sα and the EGF
receptor (EGFR) protein tyrosine kinase activity (Nair, BG, Parikh, B., Milligan, G., and Patel,
TB (1990) J. Biol. Chem. 265, 21317-21322; Nair, BG, and Patel, TB (1993) Biochem.
Pharmacol. 46, 1239-1245). Therefore, studies were performed to investigate the hypothesis
that the EGFR protein tyrosine kinase phosphorylates G sα and activates this protein …
