The Popdc gene family in the rat: molecular cloning, characterization and expression analysis in the heart and cultured cardiomyocytes
D Parnes, V Jacoby, A Sharabi, H Schlesinger… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Three Popeye domain-containing (Popdc 1–3) family-members are known in vertebrates.
Their exact function is as yet unknown although involvement in cell adhesion has been
suggested. We report herein sequencing of the rat Popdc 1–3 cDNAs that show high
homology to other vertebrate orthologs and are expressed primarily in the heart and skeletal
muscles. Popdc2 splice variants were identified, with Popdc2C showing a distinctive age-
dependent decline. In isolated cardiomyocytes, Popdc genes were negatively regulated by …
Their exact function is as yet unknown although involvement in cell adhesion has been
suggested. We report herein sequencing of the rat Popdc 1–3 cDNAs that show high
homology to other vertebrate orthologs and are expressed primarily in the heart and skeletal
muscles. Popdc2 splice variants were identified, with Popdc2C showing a distinctive age-
dependent decline. In isolated cardiomyocytes, Popdc genes were negatively regulated by …
