Determinants and patterns of survival in adenoid cystic carcinoma of the head and neck, including an analysis of adjuvant radiation therapy

S Lloyd, BY James, LD Wilson… - American journal of …, 2011 - journals.lww.com
Objectives: The effect of adjuvant radiation therapy (RT) on survival in patients with adenoid
cystic carcinoma (ACC) is much debated. Studies with large numbers of patients and long
follow-up are lacking in the literature. Methods: We identified 2286 single-primary ACCs of
the head and neck treated with surgery in the National Cancer Institute's surveillance,
epidemiology, and end results database. The determinants of survival, including the effect of
adjuvant RT, were analyzed with a Cox Proportional Hazards Model. Results: The overall 5 …