Contrast-induced nephropathy in CT: incidence, risk factors and strategies for prevention

SM Tao, JL Wichmann, UJ Schoepf, SR Fuller… - European …, 2016 - Springer
SM Tao, JL Wichmann, UJ Schoepf, SR Fuller, GM Lu, LJ Zhang
European radiology, 2016Springer
In the past, a high percentage of hospital-acquired renal failure was attributed to contrast
media. That position is now very controversial. Recently, doubts have been raised regarding
the real relationship between acute kidney injury and intravenous contrast media
administration. Similarly, statements about specific methods of preventing contrast-inducing
nephropathy have been challenged. This review article addresses the controversies of
incidence, causation, and prevention in an attempt to help the practicing radiologist adopt …
Abstract
In the past, a high percentage of hospital-acquired renal failure was attributed to contrast media. That position is now very controversial. Recently, doubts have been raised regarding the real relationship between acute kidney injury and intravenous contrast media administration. Similarly, statements about specific methods of preventing contrast-inducing nephropathy have been challenged. This review article addresses the controversies of incidence, causation, and prevention in an attempt to help the practicing radiologist adopt methods for their own department.
Key Points
The reported CIN incidence ranges from 2–12 % following contrast-enhanced CT.
Studies without a non-contrast CT control group may overestimate CIN incidence.
Development and application of a comprehensive CIN prevention strategy is recommended.
Springer